1.
Spina Bifida latin word for
split spine.
2.
Most common group of birth
defects called neural tube defects (NTD).
3.
The neural tube develops into
the brain and spinal cord.
What
is Spina Bifida?
It’s a defect of the spine in a developing fetus, it affects the brain, spinal
cord, and it’s muscles surrounding it, and resulting in loss of movement and or
sensation to the legs and feet as well as bowel movement and bladder
dysfunction.
When
does Spina Bifida occur?
The
notochord is a column of cells that run up the length of the embryo between the
ectoderm and endoderm. It plays an important role in inducing formation of the
spinal cord and spinal column. The mesenchymal rods run down the length of the
embryo form lateral to the notochord by the concentration of mesenchymal cells.
The rods eventually break into 42-44 pairs of somites at sequential levels.
Somites will form part of the vertebrae by migrating around the neural tube,
other parts of the mesenchyme will form tissue such as muscle,posterior
vertebral arch and ligaments behind the spinal cord.
Three
forms of Spina Bifida
1.
Occulta-There is a small defect
or gap in one or more vertebrae of the spine, most affected individuals have no
problems.
2.
Meningocele-Rarest form a cyst
consisting of membranes surrounding the spinal cord pokes through the open part
of the spine. Can be removed surgically allowing for normal development.
3.
Myelomeningocele- Most severe
form. The cyst holds both membranes surrounding the spinal canal, nerve roots
of the spinal cord and often the cord itself. Sometimes it’s a fully exposed
section of the spinal cord and nerves. Has to be closed surgically. In spite of
surgery the problem of paralysis,bladder and bowel control still remain.
What
causes Spina Bifida?
Spina
bifida is usually an isolated birth defect. Although scientists believe
genetics and environmental factors act together to cause this, many babies born
with spina bifida have no family history of this disorder. Women with certain
chronic health problems such as diabetes and seizure disorders have an
increased risk of having a baby with spina bifida especially if taking
anticonvulcant medications. Approximately 1/100 of having a baby with spina
bifida.
How
Is Spina Bifida treated?
One way that Spina Bifida is being treated
is by operating on the fetus while still in the womb. This procedure is done as
if fetus is being delivered via cesarean section.
Another way is that it is usually treated
surgically between 24 to48 hours after birth.
Can
Spina Bifida be prevented?
Yes it can, studies have showed that women
should take folic acid before and during pregnancy to avoid any neural tube
defects.It is recommended that women take a multivitamin containing 400
micrograms of folic acid daily and foods that contain natural folic acid such
as vegetables, grains, and orange and citrus juices.
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