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Wednesday, October 12, 2016

Alzheimer Disease problem


Bismillahirahmanirahim , Alzheimer's disease is a progressive brain disorder and irreversible that slowly destroys memory (memory) and the ability to think, and ultimately impair the ability to carry out simple tasks everyday. In most people with Alzheimer's disease, the first symptoms appeared in the mid-60s.



Alzheimer's is a disease which is the most common cause of dementia in the elderly. Dementia is a loss of cognitive function; thinking, remembering, and reasoning and the ability to behave in such a way that interfere with a person's life or daily activities. Dementia appears in various stages; ranging from mild, when only slightly impaired brain function and has just started, can lead to the most severe stage, when a person can no longer self-sufficient and must rely entirely on others for simple daily activities.

History of Alzheimer.
Alzheimer's disease is named after Dr. Alois Alzheimer. In 1906, Dr. Alzheimer see changes in the brain tissue of a woman who had died of an unusual mental illness. Her symptoms include memory loss, language problems, and unpredictable behaviour. After he died, Dr. Alzheimer examine his brain and found many abnormal clumps (now called amyloid plaques) and tangled bundles of fibres (now called neurofibrillary, or tau, tangles). Plaques and tau in the brain is still regarded as a major sign of Alzheimer's disease. Another sign is the loss of connections between nerve cells (neurons) in the brain. We know that neurons transmit messages between neurons with each other in our brain, and distribute the signal from the brain to the muscles and organs of the body, it does not run smoothly on Alzheimer's disease.

Recognize the symptoms of Alzheimer
Impaired memory is one of the first signs of cognitive impairment associated with Alzheimer's disease. In general, people who have mild memory disorder known as mild cognitive impairment or mild cognitive impairment (MCI). At MCI, the person has memory problems more severe than normal according to the standard of his age, but symptoms are not to interfere with daily life. Parents with MCI are at greater risk for developing Alzheimer's. If this happens, Alzheimer's disease memory disturbance would disrupt daily life. The first symptoms of Alzheimer's disease varies from person to person. For most people, the initial symptoms can include memory lost, but others that first appeared precisely the aspect of non-memory, such as a problem with the pronunciation of words, vision / spatial issues, and impaired reasoning or judgment.
  
What is the difference with ordinary forgotten?
Become a normal thing if someone occasionally forget about something. The more we age, the more decreases a person's ability to remember words or names, or forget to put something. Occasionally forget not necessarily indicate dementia or Alzheimer's, Or senile dementia caused by Alzheimer's disease will show an unnatural forget, like do not recognize the face or the previous name is familiar, difficulty performing common tasks (such as using the telephone or the way home), or not being able to remember information just given.

What is the Cause ?
The cause of Alzheimer Scientists do not yet fully understand what causes Alzheimer's disease in most people. Alzheimer's disease that strikes young people, usually caused by genetic mutations. While Alzheimer's in the elderly in general arise from a series of complex brain changes that occur over several decades. The cause of Alzheimer's is a combination of genetic, environmental factors, and lifestyle. Although the cause is not fully understood, but the effect on the brain clearly visible. In Alzheimer damage or even killing brain cells.


Brain affected by Alzheimer's disease has a number of nerve cells are less and the relationship between nerve cells are also less, even cells surviving less than a healthy brain. This condition causes the brain size is shrinking and of course its function also decreased significantly.

How to diagnoses ?
Doctors use several methods and special tools to help determine whether someone is experiencing memory problems were suffering from "dementia is Alzheimer's" or dementia may be due to other diseases.

To diagnose Alzheimer's, doctors can do the following:
·         Requesting information from a family member or someone at home about overall health, past medical problems, the patient's ability to carry out daily activities, changes in behavior and personality.
·         Behavioral tests of memory, problem solving, attention, counting, and language .
·         Conducting medical tests standards, such as blood and urine tests, to identify other possible causes Doing a scan of the brain, such as computed tomography (CT scan), magnetic resonance imaging (MRI), or positron emission tomography (PET), to rule out other possible causes.


·         Various types of these checks will be repeated to give doctors information about how a person's memory and other cognitive functions change from time to time.

Treatment of Alzheimer's Disease


Alzheimer's is a complex issue, and it is impossible to just use one drug or intervention can successfully treat it. The current approach focuses on helping patients maintain mental function, managing behavioral symptoms, and slow or delay symptoms of the disease. The researchers hope to develop therapies that target the mechanisms of genetic, molecular, cellular and specific so that the actual cause of the disease can be stopped or prevented.
Several types of Alzheimer's drugs that are often used include: Cholinesterase inhibitors and Memantine, besides that it is necessary also the management of the environment, physical exercise, and nutritional aspects. Wallahuaklam.





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